SerpentinaDB: a database of plant-derived molecules of Rauvolfia serpentina
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چکیده
منابع مشابه
SerpentinaDB: a database of plant-derived molecules of Rauvolfia serpentina
BACKGROUND Plant-derived molecules (PDMs) are known to be a rich source of diverse scaffolds that could serve as a basis for rational drug design. Structured compilation of phytochemicals from traditional medicinal plants can facilitate prospection for novel PDMs and their analogs as therapeutic agents. Rauvolfia serpentina is an important medicinal plant, endemic to Himalayan mountain ranges o...
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Aldose Reductase (AR) is implicated in the development of secondary complications of diabetes, providing an interesting target for therapeutic intervention. Extracts of Rauvolfia serpentina, a medicinal plant endemic to the Himalayan mountain range, have been known to be effective in alleviating diabetes and its complications. In this study, we aim to prospect for novel plant-derived inhibitors...
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The enzyme strictosidine synthase (STR1) from the Indian medicinal plant Rauvolfia serpentina is of primary importance for the biosynthetic pathway of the indole alkaloid ajmaline. Moreover, STR1 initiates all biosynthetic pathways leading to the entire monoterpenoid indole alkaloid family representing an enormous structural variety of approximately 2000 compounds in higher plants. The crystal ...
متن کاملAntibacterial Activity and Preliminary Phytochemical Screening of Endophytic Fugal Extract of Rauvolfia serpentina
Endophytic fungi isolated from Rauvolfia serpentina, a well known Indian medicinal plant, is used in Ayurveda for treatment of many diseases. Isolated endophytes were screened for their antibacterial activity against pathogenic bacteria. Twenty fungal isolates were recovered from different parts of the host plant and they were characterized for their morphological features through Scanning Elec...
متن کاملFluorescence Analysis on the Roots of Rauvolfia Serpentina (L.) Benth. Ex Kurz Under UV Radiation
The present study deals with an analysis of the roots of Rauvolfia serpentine (L) Benth. Ex Kurz under ultraviolet radiation and also under daylight. The coarsely powdered roots were treated with various chemical reagents and the characteristic fluorescence patterns emitted were recorded and are reported in this paper. This study was undertaken as a pharmacognostic standardization to ascertain ...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2015
ISSN: 1472-6882
DOI: 10.1186/s12906-015-0683-7